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La présente invention concerne en outre des compositions et des procédés d’utilisation d’un inhibiteur d’époxyde hydrolase pour potentialiser l’effet de déplétion folliculaire de(s) isomère(s) VCD.

In addition, compositions and methods of use of an epoxide hydrolase inhibitor to potentiate the follicular depletion effect of the VCD isomer(s) are disclosed.

santé - wipo.int

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Transitional versus surgical menopause in a rodent model: etiology of ovarian hormone loss impacts memory and the acetylcholine system... The majority of women do not have their ovaries surgically removed and undergo transitional hormone loss via ovarian follicular depletion....

santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov

Publications scientifiques

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Research article folliculogenesis is not fully inhibited during gnrh analogues treatment in mice challenging their efficiency to preserve the ovarian reserve during chemotherapy in this modelAs many chemotherapy regimens induce follicular depletion, fertility preservation became a major concern in young cancer patients....

général - core.ac.uk - PDF: www.plosone.org

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Histopathologic alterations associated with the transplanted homologous dog liver... Lymph nodes, in addition, were characterized by cortical and follicular depletion....

général - core.ac.uk - PDF: d-scholarship.pitt.edu

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Ovarian ageing and the impact on female fertility [version 1; referees: 2 approved]... The pattern of follicular depletion as well as the factors, timing and mechanisms surrounding both declining oocyte number and oocyte quality remain incompletely understood....

général - core.ac.uk - PDF: doaj.org

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Depletion of ovarian follicles with age in chimpanzees: similarities to humans1... The follicular depletion rate in this sample was indistinguishable from that shown across the same ages in classic human data sets....

général - core.ac.uk - PDF: www.umass.edu