Subependymal zone-derived oligodendroblasts respond to focal demyelination but fail to generate myelin in young and aged mice.... In the aged CC their mitotic activity is much reduced, although they still act as a “fast-response element” to focal demyelination....
Subependymal zone-derived oligodendroblasts respond to focal demyelination but fail to generate myelin in young and aged mice... In the aged CC their mitotic activity is much reduced, although they still act as a “fast-response element” to focal demyelination....
Mri-guided intracerebral convection-enhanced injection of gliotoxins to induce focal demyelination in swine... The goal of the current study was to establish a model of focal demyelination in the brain of domestic pig using MRI-guided gliotoxin delivery....
Supplementary material for: microglial activation induces generation of oligodendrocyte progenitor cells from the subventricular zone after focal demyelination in the corpus callosum... This study revealed that focal demyelination in the corpus callosum caused activation of the microglia, not only at the site of demyelination but also in the SVZ, and dramatically increased the generation...
