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carcinome arsenical

Dna hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy... Further, hypermethylation of p53 gene was also observed in arsenic-induced skin cancer patients compared to subjects having skin cancer unrelated to arsenic, though not at significant level....

général - core.ac.uk - PDF: toxsci.oxfordjournals.org

Arsenic induces p62 expression to form a positive feedback loop with nrf2 in human epidermal keratinocytes: implications for preventing arsenic-induced skin cancer... Our findings indicate that arsenic induces p62 expression to regulate the Nrf2 pathway in human keratinocytes and suggest that targeting p62 may help prevent arsenic-induced skin cancer

PDF: doaj.org

Nicotinamide enhances repair of arsenic and ultraviolet radiation-induced dna damage in hacat keratinocytes and ex vivo human skin.Arsenic-induced skin cancer is a significant global health burden....

PDF: doaj.org