Peg-like nanoprobes: multimodal, pharmacokinetically and optically tunable nanomaterials.... PN's were used to image brain capillary angiography (intravital 2-photon microscopy), tumor capillary permeability (intravital fluorescent microscopy), and the tumor enhanced permeability and retention (EPR) effect (111In-PN and SPECT)....
Peg-like nanoprobes: multimodal, pharmacokinetically and optically tunable nanomaterials... PN’s were used to image brain capillary angiography (intravital 2-photon microscopy), tumor capillary permeability (intravital fluorescent microscopy), and the tumor enhanced permeability and retention (EPR) effect (111In-PN and SPECT)....
Ccording to world health organization estimates,... Glioblastomas multiforme are biologically aggressive tu-mors that present unique treatment challenges due to the fol-lowing characteristics: 1) localization of tumors in the brain; 2) intrinsic resistance of these lesions to conventional ther-apy; 3) limited capacity of the brain to repair itself; 4) the spread of malignant cells into brain parenchyma; 5) the vari-ably disrupted blood–brain barrier complicating drug deliv-ery; 6) tumor capillary leakage, with resultant peritumoral edema and intracranial hypertension; 7) the limited res-ponse to therapy; and 8) the neurotoxicity of treatments di
Effects of hydroxy safflower yellow-a on tumor capillary angiogenesis in transplanted human gastric adenocarcinoma bgc-823 tumors in nude mice AbstractObjectiveTo study the effects of hydroxy safflower yellow A (HSYA) on tumor capillary angiogenesis in transplanted human gastric adenocarcinoma BGC-823 tumors in nude mice.MethodsBGC-823...
