The double-stranded antisense agent further comprises a complementary strand annealed to the antisense strand.
These are oligodeoxynucleotides consisting of an antisense-strand homologous to the viral RNA and a second strand, partially complementary to the antisense-strand.
More particularly, the modified siRNA comprises a sense strand and an antisense strand, wherein the sense strand contains a mosified RNA nucleotide in at least one of positions 8-14, calculated from the 5’-end.
The present invention is directed to novel DNA-RNA hybrids comprising either a DNA sense strand and an RNA antisense strand, or an RNA sense strand and a DNA antisense strand.
The forward probe is complementary to an inner sequence of the target sense strand, and the reverse probe is complementary to an inner sequence of the target antisense strand.
By using the cDNA mixture, sense strand/antisense strand cRNA is synthesized by T7 and SP6 polymerases.
The present invention is directed to novel DNA-DNA hybrids comprising a DNA sense strand and a DNA antisense strand.
The forward primer binds to the anti-sense cDNA strand and produces a dsDNA target.
Additionally, a strand of RNA called antisense RNA can set with a complementary strand of mrna and block interpretation.
The antisense compounds may be single- or double-stranded and are targeted to nucleic acid encoding eIF4E.
For example, a SNP genotype that is G G on the forward strand will be C C on the reverse strand.
Activation of the toxin depends upon hybridization of the antisense strand with the target nucleic acid.
Accordingly, the present invention provides an isolated siRNA comprising a sense RNA and an antisense RNA strand or a single strand.
The present invention relates to a method for producing antisense molecules by using bacteriophages with closed single stranded genome and antisense molecules produced thereby.
The present invention describes a method of 8-color sequencing.
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