The race against protease activation defines the role of escrts in hiv budding.... We show that compromised interactions with ESCRTs result in delayed budding of virions from host cells....
The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency.... We examined the interaction between the processing of the human immunodeficiency virus type 1 Gag precursor and the membrane-based assembly and budding of virions....
Asymmetric budding of viruses in epithelial monlayers: a model system for study of epithelial polarity.... of two different lines of polarized epithelial cells grown as monolayers with several types of enveloped viruses results, for each virus type, in a characteristic asymmetric budding of virions....
Ultrastructural analysis of c/ok virus isolate in cell culture as observed by negative stain (a) and thin-section (b) electron microscopy.... Note assembly and budding of virions at the apical pole....