The two main types of thalassemia are alpha thalassemia and beta thalassemia, depending on which chains of hemoglobin are defected.
Beta thalassemia minor occurs when only one of the beta chains is defected.
Despite genetic counselling, there are still a significant number of children suffering from beta thalassaemia and other genetic haemoglobinopathies.
Study compares effectiveness and cost of gene therapy and HSCT in major beta-thalassemia
Beta thalassemia minor is associated with minimal symptoms and generally does not require any intervention.
However, heart complications arising from beta thalassemia major can make this condition fatal before the age of 30 years.
However, heart complications arising from beta thalassemia major can make this condition fatal before the age of 30 years.
Another potential application of this finding, added Blobel, may be in another inherited blood disorder, beta-thalassemia, also involving abnormal hemoglobin.
Beta thalassaemia major is one of the most severe forms of chronic congenital anaemia caused by a genetic deficiency in the production of haemoglobin.
Both alpha- and beta-thalassemia are more prevalent in tropical and subtropical regions of the world, particularly where malaria is or has been endemic.
The mother should be assessed by a cardiologist or hematologist before and during pregnancy, to minimize problems, especially if she has thalassemia beta minor.
This study does a critical comparison of both cost and outcomes for patients with beta-thalassaemia, whose primary alternative to gene therapy would be hematopoietic stem cell transplantation.
Thalassemia is classified as Alpha Thalessemia or beta Thalessemia.
The disease is defined as alpha thalassaemia or beta thalassaemia accordingly.
There are two different types of thalassemia: alpha thalassemia, beta thalassemia.
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