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bénidipine

benidipine

chimie / santé - iate.europa.eu
L'invention concerne une composition d'hydrochlorure de bénidipine médicinale possédant la propriété de permettre la dissolution rapide pour l'accélération de l'absorption rapide de l'hydrochlorure de bénidipine en tant que médicament principal.

A medicinal benidipine hydrochloride composition which has the property of enabling rapid dissolution for accelerating the rapid absorption of benidipine hydrochloride as the main drug.

santé - wipo.int
La présente invention concerne des nanoparticules de chlorhydrate de bénidipine et leur procédé de préparation au moyen de techniques ultrasonores.

A method to prepare nanoparticles of benidipine hydrochloride and the preparation method thereof via ultrasonic techniques are disclosed.

chimie - wipo.int
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A ca channel blocker, benidipine, increases coronary blood flow and attenuates the severity of myocardial ischemia via no-dependent mechanisms in dogs ... This study was undertaken to examine whether a dihydropyridine Ca channel blocker, benidipine, increases cardiac NO levels, and thus coronary blood flow (CBF) in ischemic hearts.Background....
général - core.ac.uk -
Anti-apoptotic effect of benidipine, a long-lasting vasodilating calcium antagonist, in ischaemic/reperfused myocardial cells... The present study investigated the effects of benidipine, an L-type calcium channel blocker, on myocardial infarct size, apoptosis, necrosis and cardiac functional recovery in rabbits subjected to myocardial ischaemia/reperfusion...
 PDF: www.pubmedcentral.nih.gov
Identification, synthesis and characterization of process related impurities of benidipine hydrochloride, stress-testing/stability studies and hplc/uplc method validationsBenidipine hydrochloride, used as an antihypertensive agent and long-acting calcium antagonist, is synthesized for commercial use as a drug substance in highly pure form....
 PDF: doaj.org
Mechanisms of long-lasting effects of benidipine on ca current in guinea-pig ventricular cells.... Benidipine (KW-3049), a new derivative of 1,4-dihydropyridine (DHP), showed dose-dependent inhibition of Ca current (ICa) which was elicited by depolarization from -40 mV to +10...
 PDF: www.pubmedcentral.nih.gov
Characterization of benidipine and its enantiomers ’ metabolism by human liver cytochrome p450 enzymesBenidipine is a dihydropyridine calcium antagonist that has been used clinically as an antihypertensive and antianginal agent....
 PDF: dmd.aspetjournals.org


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