Modulation of calcium channel currents in guinea-pig single ventricular heart cells by the dihydropyridine bay k 8644.... The peak times of the Ba2+ currents were diminished over the voltage range tested between -40 and +20 mV after Bay K 8644 in parallel with a shortening of the time constant of activation that was estimated from fits of the recorded currents with a d2f model....
Allosteric mek1/2 inhibitor refametinib (bay 86-9766) in combination with sorafenib exhibits antitumor activity in preclinical murine and rat models of hepatocellular carcinoma ... On the signaling pathway level, the combination of BAY 86-9766 and sorafenib led to inhibition of the upregulatory feedback loop toward MEK phosphorylation observed after BAY 86-9766 monotreatment....
Spatially discordant alternans in cardiomyocyte monolayers... After BAY K 8644 (n 28), conduction velocity restitution becam
Bay-11-7082 treatment results in nf-κb inhibition and decreased invasiveness in breast cancer cells.... Quantification of the number of MDA-MB-231 (E) and SUM159 cells (F) penetrated the matrigel showed a decreased invasiveness in breast cancer cells after Bay-11-7082 treatment (n = 3; ** p≤0.01)....
