The invention relates in particular to a CA125-specific anti-anti-idiotypic antibody which reacts with anti-idiotypic anti-body ACA125.
The present invention further provides an anti-idiotypic monoclonal antibody which mimics taxol.
Additionally, this invention provides a method of producing the anti-idiotypic monoclonal antibody.
The present invention provides an anti-idiotypic monoclonal antibody which specifically induces an immune response against a glycosphingolipid.
The 1F7 antibody is an effective immune modulator that has anti-idiotypic binding affinity for anti-HIV antibodies.
The present invention relates to an anti-idiotype antibody that mimics the disialoganglioside GD2.
The anti-idiotype antibody blocks integrin function on newly growing vessels, endothelial cells, or tumor cells.
Thus, monoclonal or polyclonal anti-idiotype antibody of disintegr'iin can be administered to a patient in need of anti-angiogenic or anti-metastatic therapy.
The present invention further provides an antibody which is an anti-idiotype of the monoclonal antibody.
Additionally, the present invention provides a cell line capable of producing an anti-idiotype murine antibody specific for the anti-CD22 antibodies.
Anti-idiotypic antibodies means antibodies which bind to the specific antigen binding sites of other antibodies
An antibody having the region as an epitope is very useful as an immunogen in the production of an anti-idiotypic antibody.
Anti-idiotypic antibodies means antibodies which bind to the specific antigen binding sites of other antibodies
The invention also relates to a pharmaceutical composition that can be used to prevent or inhibit angiogenesis comprising at least one such anti-idiotypic antibody.
Anti-idiotypic antibodies means antibodies which bind to the specific antigen binding sites of other antibodies
Anti-idiotypic antibodies means antibodies which bind to the specific antigen binding sites of other antibodies
Anti-idiotypic antibodies means antibodies which bind to the specific antigen binding sites of other antibodies
The present invention describes the generation of an anti-idiotype single-chain Fv (scFv) antibody specific for the murine (RFB4), chimeric (SM03) and humanized (SM06) versions of an anti-CD22 antibody (the anti-CD22 antibodies).
An anti-idiotypic monoclonal antibody, which induces production of mucoid exopolysaccharide-specific antibodies which are opsonic for mucoid Pseudemonas aeruginosa.
The anti-idiotypic monoclonal antibody is produced by a cell line designated C9F5 and having ATCC Accession No. HB 10715.
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