In silico prediction of ebolavirus rna polymerase inhibition by specific combinations of approved nucleotide analogues... We present an in silico study as a first step to identify inhibitors of ebolavirus polymerase activity based on approved antiviral nucleotide analogues....
Telbivudine (sebivo) in patients with hepatitis b virus (hbv) chronic infection... At the moment, there are 4 approved antiviral drug classes, with different antiviral efficacy, for the treatment of chronic hepatitis B: interferons, nucleoside analogues, nucleotide analogues, and cyclopents.The...
Development of a comprehensive set of p2 receptor pharmacological research compounds... Initial purinergic signalling research made use of compounds based on pyridoxal phosphate, suramin and nucleotide analogues; recently developed compounds are often derivatives of these early tools....
Sofosbuvir as backbone of interferon free treatments AbstractSofosbuvir is the first-in-class NS5B nucleotide analogues to be launched for hepatitis C virus (HCV) treatment....
