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amsacrine

santé / chimie - iate.europa.eu
Relation of in vitro colony survival to clinical response in a prospective trial of single-agent chemotherapy for metastatic melanoma.... A number of agents were used in these evaluations, including actinomycin D, Amsacrine, bisantrene, mitoxantrone, BCNU, vinblastine, vindesine, 5-fluorouracil, MGBG, etoposide, interferon, tamoxifen, and 13-cis-retinoic acid....
santé - core.ac.uk - PDF: escholarship.org
Activity of topoisomerase inhibitors against pneumocystis carinii in vitro and in an inoculated mouse model. antimicrob. agents chemotherFive topoisomerase H inhibitors (amsacrine [m-AMSAJ, two epipodophyllotoxins, and two quinolones) and the alkaloid camptothecin (a topoisomerase I inhibitor) were evaluated to assess their activities against ...

Publications scientifiques

Role of minor groove width and hydration pattern on amsacrine interaction with dnaAmsacrine is an anilinoacridine derivative anticancer drug, used to treat a wide variety of malignancies....
général - core.ac.uk - PDF: ftp:
Inhibition of cardiac herg currents by the dna topoisomerase ii inhibitor amsacrine: mode of action... The topoisomerase II inhibitor amsacrine is used in the treatment of acute myelogenous leukemia....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Amsacrine analog-loaded solid lipid nanoparticle to resolve insolubility for injection delivery: characterization and pharmacokinetics...Hospital, 5School of Medicine, Medical College, China Medical University, Taichung, 6Department of Neurology, China Medical University An-Nan Hospital, Tainan, Taiwan Abstract: Amsacrine analog is a novel chemotherapeutic agent that provides potentially broad antitumor activity when compared to traditional amsacrine....
général - core.ac.uk - PDF: doaj.org


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