Dictionnaire français - anglais

altéplase

général / santé - eur-lex.europa.eu iate.europa.eu
Rapilysin a été comparé à d'autres médicaments utilisés pour dissoudre les caillots sanguins: streptokinase (6 000 patients) et altéplase (environ 15 000 patients).

Rapilysin has been compared with other medicines used in thrombolysis: streptokinase (6,000 patients) or alteplase (about 15,000 patients).

général - CCMatrix (Wikipedia + CommonCrawl)
Rapilysin a été comparé à d'autres médicaments utilisés pour dissoudre les caillots sanguins: streptokinase (6 000 patients) et altéplase (environ 15 000 patients).

Rapilysin has been compared with other medicines used to dissolve blood clots: streptokinase in 6,000 patients and alteplase in about 15,000 patients.

général - CCMatrix (Wikipedia + CommonCrawl)
Nombre et pourcentage de femmes qui subissent un AVC ischémique en phase aiguë pendant la grossesse qui reçoivent un traitement par altéplase par voie intraveineuse.

Number and percentage of women who experience an acute ischemic stroke during pregnancy who are administered intravenous alteplase.

général - CCMatrix (Wikipedia + CommonCrawl)
les patients sont admissibles à la thrombolyse (altéplase par voie intraveineuse) dans les 4,5 heures après le début connu ou présumé des symptômes [niveau de preuve B];

patients are eligible for medical thrombolysis (intravenous alteplase) within 4.5-hours of known or presumed symptom onset [Evidence Level B];

général - CCMatrix (Wikipedia + CommonCrawl)
Prendre le médicament anti-caillot altéplase dans les 90 minutes suivant un accident vasculaire cérébral “donne aux patients plus de deux fois la chance de guérison complète”, a déclaré le Daily Mail.

Taking the clot-busting drug alteplase within 90 minutes of a stroke “gives patients more than double the chance of full recovery”, said the Daily Mail.

général - CCMatrix (Wikipedia + CommonCrawl)
Predictors of clinical outcome in patients receiving local intra-arterial thrombolysis without subsequent symptomatic intracranial hemorrhage against acute middle cerebral artery occlusion... No benefits were shown in the Alteplase Throm
santé - core.ac.uk - PDF: www.ajnr.org
Interventional and conservative treatment effectiveness in thrombolysed patients with myocardial infarction... In total, 40 patients in acute MI phase underwent systemic thrombolysis with alteplase or streptokinase....
 PDF: doaj.org
A journal of neurology letter to the editor reply: intravenous thrombolysis for ischaemic strokes: a call for reappraisal... Aside from well documented limitations, recombinant tissue plasminogen activator (rt-PA, alteplase) remains the only evi-dence-based treatment in acute ischaemic stroke (Balami et al.,...
altéplase
santé - iate.europa.eu
santé - iate.europa.eu
santé - iate.europa.eu

Publications scientifiques

Effect of the pleiotropic drug cnb-001 on tissue plasminogen activator (tpa) protease activity in vitro: support for combination therapy to treat acute ischemic strokeCurrent state-of-the-art acute ischemic stroke clinical trials are designed to study neuroprotectants when administered following thrombolysis; tissue plasminogen activator (tPA) is administered to patients within 3–4.5...
santé - core.ac.uk - PDF: ftp:
Original article-neuroscience www.cmj.ac.kr intra-arterial thrombolysis after full-dose intravenous tpa via the “drip and ship ” approach in patients with acute ischemic stroke: preliminary reportAccording to the “drip and ship ” concept, patients who are not responsive to intravenous tissue plasminogen activator (IV-tPA) at a community hospital may be candidates for subsequent intra-arterial (IA) thrombolysis at a comprehensive stroke center....
santé - core.ac.uk - PDF: citeseerx.ist.psu.edu
Trends in thrombolytic use for ischemic stroke in the united statesBACKGROUND: Although recombinant tissue plasminogen activator (tPA) improves outcomes from ischemic stroke, prior studies have found low rates of administration....
santé - core.ac.uk - PDF: hdl.handle.net
Treatment with recombinant tissue plasminogen activator (r-tpa) induces neutrophil degranulation in vitro via defined pathways ... Here, we investigated the effects of recombinant tissue plasminogen activator (r-tPA) on neutrophil pathophysiology in vitro and in a case–control study with AIS patients submitted (n=60) or not (n=30) to thrombolysis....
santé - core.ac.uk -
The fibrinolytic system attenuates vascular tone: effects of tissue plasminogen activator (tpa) and aminocaproic acid on renal microcirculation... The renal medulla is a major source of tpale">plasminogen tpale">activators (PA), recently shown to induce vasodilation in vitro....
santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov

Traductions en contexte français - anglais

La mortalité à 30 jours est plus faible sous altéplase que chez les patients ne recevant aucun traitement thrombolytique.

30-day-mortality is reduced as compared to patients not undergoing thrombolytic therapy.

général - CCMatrix (Wikipedia + CommonCrawl)
Le taux de reperméabilisation du vaisseau lésé a été supérieur chez les patients sous altéplase que chez ceux traités par la streptokinase, 60 et 90 minutes après la thrombolyse.

Actilyse-treated patients showed higher infarct related vessel patency rates at 60 and 90 minutes after thrombolysis than the streptokinase-treated patients.

général - CCMatrix (Wikipedia + CommonCrawl)


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