Pharmacokinetics of a fluoronaphthyridone, trovafloxacin (cp 99,219), in infants and children following administration of a single intravenous dose of alatrofloxacinThe pharmacokinetics of trovafloxacin following administration of a single intravenous dose of alatrofloxacin, equivalent to 4 mg of trovafloxacin per kg of body weight, were determined in 6 infants (ages 3 to 12 months) and 14 children (ages, 2 to 12 years)....
Oral bioavailability and pharmacokinetics of trovafloxacin in patients with aids... By using a randomized design, single 200-mg doses of oral trovafloxacin and intravenous alatrofloxacin were administered....
Comparison of levofloxacin, alatrofloxacin, and vancomycin for prophylaxis and treatment of experimental foreign-body-associated infection by methicillin-resistant staphylococcus aureusThe prophylactic and therapeutic activities of two fluoroquinolones, levofloxacin and alatrofloxacin (the l-Ala-l-Ala prodrug of trovafloxacin), were compared to those of vancomycin in two different experimental models of foreign-body-associated infections caused...
Copyright © 1997, american society for microbiology penetration of trovafloxacin into cerebrospinal fluid in humans following intravenous infusion of alatrofloxacin...determine concentrations of trovafloxacin (CP-99,219) achieved in the cerebrospinal fluid (CSF) relative to those in the serum of healthy subjects after intravenous infusion of alatrofloxacin (CP-116,517), the alanyl-alanyl prodrug of trovafloxacin....
