Examples of such antagonists include ActRIIB polypeptides, anti-ActRIIB antibodies, anti-myostatin antibodies, anti-GDF3 antibodies, anti-Nodal, anti-activin, and anti-GDF11 antibodies.

Chorionic gonadotropin is the result of the interaction of sex steroids, cytokines, releasing hormone, growth factors, inhibin and activin.

Furthermore, a method for identifiying a TMEFF2 modulator comprising determing whether said TMEFF2 modulator is capable of reducing the binding between Activin and TMEFF2 is contemplated.

In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density using anti-activin antibodies.

The disclosure provides an assay system for evaluating compounds that modulate Smad3-mediated gene regulation, and the TGF-β/activin signaling pathway, in particular.

Researchers found that following loss of or damage to myelin, macrophages can release a compound called activin-A, which activates production of more myelin.

A presently preferred member of the invention superfamily of receptors binds specifically to activins, in preference to inhibins, transforming growth factor-β, and other non-activin-like proteins.

It inhibits the molecules that connect to receptors on the cell surface called activin type IIB Receptor (ActRIIB).

This invention relates to growth media for the culture of pluripotent stem cells, in particular embryonic stem (ES) cells, which comprise a β-catenin/P300 antagonist and an Activin/TGFβ ligand.

Its primary function in the body is bioneutralization of members of the TGF-β superfamily, with a particular focus on activin and paracrine hormones.

Examples of such antagonists include ActRIIB polypeptides, anti-ActRIIB antibodies, anti-activin A and/or B antibodies, anti-myostatin antibodies, anti- GDF3 antibodies, and anti-BMP7 antibodies.

GnRH synthesis regulates the concentrations of testosterone, estradiol, dihydrotestosterone, as well as blood levels of leptin, activin, prolactin and inhibin.

Its primary function in the body is bioneutralization members of the TGF-β family of proteins, with special focus on activin and paracrine hormones.

She is particularly interested in a chain-reaction series of molecular events known as the TGF-beta/Activine signaling pathway, which plays a major role in tumorous cell proliferation.

Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.