The antisense molecules and compositions comprise nucleic acid molecules, such as RNA, DNA, or nucleic acid molecules with modified backbones, such as PNA.

The antisense molecules and compositions comprise nucleic acid molecules, such as RNA, DNA, or nucleic acid molecules with modified backbones, such as PNA.

The invention relates to a process for the preparation of at least one solid phase bound peptide, PNA or a chimera.

PNA is a very stable molecule with very high affinity for nucleic acid allowing a PNA probe to be shorter than conventional nucleic acid probes.

In one embodiment, the genetic recognition reagent is a peptide nucleic acid (PNA) or gamma PNA (?PNA) oligomer.

The invention relates to peptide nucleic acid (PNA) conjugates which are suitable for the treatment of diseases associated with HIV, the peptide nucleic acid (PNA) inhibiting the gene expression of HIV.

A method is disclosed for the preparation of novel PNA synthons compatible with DNA synthetic reagents and instrumentation.

A peptide nucleic acid of subgroup J avian leukosis virus and uses thereof are provided.

The present invention relates to a peptide nucleic acid (PNA) conjugated with multi-amine linkers, and a method to prepare the same and utilization thereof.

The invention provides a conjugate comprising a peptide nucleic acid molecule, wherein the peptide nucleic acid molecule is conjugated to two identical fluorophores through peptidic linkers.

The present invention relates to a new method of delivery of molecules into a cell through the use of a modified signal peptide to which a peptide nucleic acid is linked.

A delivery system for delivering oligonucleotides includes a conjugate includes a complexing agent including an oligonucleotide, a peptide nucleic acid or chimera thereof and a polymer covalently attached to the complexing agent.

Peptide nucleic acid monomers are provided having chirality in their backbones, as are synthetic methods therefor and peptide nucleic acid oligomers prepared therefrom.

Provided herein are biosensors that comprise a biological signal source linked to a substrate by a peptide nucleic acid spacer and methods of use of the biosensor.

Described is a diagnostic conjugate comprising (a) a transmembrane module (TPU), (b) an address module (AS), preferably an antisense peptide nucleic acid (PNA), and (c) a signalling module (SM).