test for chromosomal aberrations in vitro

ability to induce chromosonal aberrations

Specifically, the invention relates to techniques for the detection of chromosomal aberrations and the detection of tumor specific gene products exclusively expressed by tumor cells containing said chromosomal aberrations.

Structural Changes in Chromosomes (Chromosomal Aberrations):

Congenital Human Anomalies Due to Chromosome Aberrations.

Toluene-exposed workers and chromosome aberrations.

The purpose of the in vitro chromosome aberration test is to identify agents that cause structural chromosome aberrations in cultured mammalian somatic cells.

This in vivo cytogenetic test detects chromosome aberrations in spermatogonial mitoses.

At least 100 cells should be analysed for each animal.

The banding pattern allows the identification of chromosomal aberrations.

Intratumor Morphological Heterogeneity of Cancer is Not Related to Chromosome Aberrations

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Chromosome preparations are then made from germ cells and stained, and metaphase cells are analysed for chromosome aberrations.

This damage typically ranges in scale from the losses of the entire gene to karyotypically visible chromosome aberrations.

number of cells with chromosome aberrations and type of chromosome aberrations given separately for each treated and control culture