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Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. spontaneous release of leukotriene b4 by alveolar macrophages.... Consistent with this hypothesis, incubation of normal macrophages with human neutrophil elastase resulted in the release of the same neutrophil chemotactic mediator...
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust... Collectively, ODE increased airway inflammatory cells and chemotactic mediator release in allergic (OVA) sensitized mice to suggest that persons with allergy/asthma be identified and warned prior to the occupational exposure of potentially worsening airway disease
Cyclic amp enhancing drugs modulate eicosanoid release from human alveolar macrophages... Present results indicate that drugs which enhance cAMP level decrease PGE2 release from COPD macrophages and stimulate the release of LTB4 a chemotactic mediator involved in bronchial inflammatory reactions

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