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Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human c-raf kinase supports an antisense mechanism of action in vivoTo determine the mechanism of action responsible for the in vivo antitumor activity of a phosphorothioate antisense inhibitor targeted against human C-raf kinase (ISIS 5132, also known as CGP69846A), a series of mismatched phosphorothioate analogs of ISIS 5132 or CGP69846A were synthesized...
santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov

Publications scientifiques

Measurement of mirna by qpcr after antisense inhibitor transfection does not reliably measure the level of the cellular mirna.qPCR of miR-200a and miR-125b in MCF7 cells following transfection with antisense miR-200a (antisense inhibitor), or after its addition post lysis (doping), or both....
général - core.ac.uk - PDF: figshare.com
Activation of mir-29a in activated hepatic stellate cells modulates its profibrogenic phenotype through inhibition of histone deacetylases 4.... Primary HSCs from both mice were treated with a miR-29a mimic and antisense inhibitor in order to analyze changes in profibrogenic gene expression and HSC activation using real-time quantitative RT-PCR, immunofluorescence staining, western blotting,...
général - core.ac.uk - PDF: doaj.org

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Exemples anglais - français

métallurgie et sidérurgie - iate.europa.eu
chimie / industries charbonnière et minière / technologie et réglementation technique / politique et structures industrielles / sciences naturelles et appliquées / santé / métallurgie et sidérurgie - iate.europa.eu
agriculture, sylviculture et pêche / sciences naturelles et appliquées / activité agricole - iate.europa.eu
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technologie et réglementation technique - acta.es


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