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Closely related mycobacterial strains demonstrate contrasting levels of efficacy as antitumor vaccines and are processed for major histocompatibility complex class i presentation by multiple routes in dendritic cells... smegmatis is processed and presented on MHC class I by in vitro-generated dendritic cells, which has implications for recombinant microbial vaccine development

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

A mutant library approach to identify improved meningococcal factor h binding protein vaccine antigens.... This approach offers the potential to discover mutant antigens that might not be predictable even with protein structural information and potentially can be applied to other microbial vaccine antigens that bind host proteins

PDF: doaj.org