A TIRAP-/- mouse lacking the function of the TIRAP gene on chromosome is constructed.

The five principal rivers of the state are Subansiri, Kameng, Lohit, Siang, and Tirap.

TIRAP polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed.

Culturally Naga, they are ethnically related to the Nocte and Konyak Naga of the Mon and Tirap districts.

It is located south of Lohit district and north of Tirap district.

Also disclosed are methods for utilizing TIRAP polypeptides and polynucleotides in therapy, and diagnostic assays for such.

These proteins are known as MyD88, Tirap (also called Mal), Trif, and Tram.

These proteins are known as MyD88, Tirap (also called Mal), Trif, and Tram.

Five such adapters have been discovered to date including MyD88, Mal (also known as TIRAP), Trif, Tram, and SARM.

Loku is the main festival of the Nocte Tribe of Tirap district and is celebrated to bid farwell to the winter.

The Khamtis, Singpos and Tangsas of Lohit and Tirap region are said to have originally migrated from Thailand and Myanmar (Burma) and follow Hinayana Buddhist practices.

Loku is the main festival of the Nocte Tribe of Tirap district and is celebrated to bid farewell to the winter.

Then it is confirmed that the responsibility to a ligand recognized by TLR2 such as a lipoprotein or a lipopeptide or a ligand recognized by TLR4 such as an endotoxin is specifically injured in this TIRAP-/- mouse.

A TIRAP-/- mouse lacking the function of the TIRAP gene on chromosome is constructed.

The five principal rivers of the state are Subansiri, Kameng, Lohit, Siang, and Tirap.