Buprenorphine can produce miosis and changes in the level of consciousness which may interfere with patient evaluation.

Buprenorphine can produce miosis and changes in the level of consciousness that may interfere with patient evaluation.

Particular caution is advised if buprenorphine is administered to patients taking or recently receiving drugs with CNS/respiratory depressant effects.

The drug is sold under the trade names SubutexTM, BuprenexTM, TemgesicTM and SuboxoneTM, which contain Buprenorphine HCl alone or in combination with Naloxone HCl.

The Buprenorphine drug is sold under the trade names Subutex™, Buprenex™, Temgesic™ and Suboxone™, which contain Buprenorphine HCl alone or in combination with Naloxone HCl.

[246] While injectable morphine was restocked in about two weeks, officials at the PNA and DPM were unsure of the reasons for the Temgesic shortage, and Temgesic remained unavailable.

Not to be given to patients who are known to be allergic to Temgesic or other opiates.

Temgesic occasionally causes significant respiratory depression (see section 4.4, Special Warnings and Precautions for Use).

[244] Additionally, there was a country wide shortage of Temgesic that had lasted over six months.

[245] One official at the PNA told Human Rights Watch that the PNA had not stocked Temgesic since 2008.