Example compositions include at least one mucin-cleaving class-2 SPATE protein.

In a specific embodiment, the transcytosis enhancer is a Serine Protease Autotransporters of Enterobactericeae (SPATE) protease.

Chairperson of the Commission of Coaching and Methods: Dietrich Spate (GER)

In a more specific embodiment, the SPATE protease is Extracellular Serine Protease Plasmid (O157)-encoded) (EspP).

Non-limiting example compositions include class-2 SPATE proteins that are capable of cleaving proteins involved in an inflammatory immune response in a patient.

^ Jeff Hecht, "Spate of rocket breakups creates new space junk", NewScientist, 17 January 2007.

^ Jeff Hecht, "Spate of rocket breakups creates new space junk", NewScientist, 17 January 2007.

In 1955, Doris Spates was born in one of the buildings the Army used to fill the air with chemicals from 1953 – 1954.

During the 1829 floods known as “The Muckle Spate” five Findhorn fishing boats rescued Forres residents.

During the 1829 floods known as "The Muckle Spate" five Findhorn fishing boats rescued Forres residents.

In 1955, Doris Spates was born in one of the buildings the Army used to fill the air with chemicals from 1953 - 1954.

In 1955, Doris Spates was born in one of the buildings the Army used to fill the air with chemicals from 1953 - 1954.

In 1955, Doris Spates was born in one of the buildings the Army used to fill the air with chemicals from 1953 – 1954.

Yet that's exactly what entrepreneur Oscar F. Spate tried to do in New York Parks in the glittering summer of 1901.

That's what entrepreneur Oscar F. Spate tried to do in the New York Parks in the summer of 1901.