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Dictionnaire français - anglais

sparsomycine

sparsomycin

chimie / général / santé - iate.europa.eu eur-lex.europa.eu

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Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to a2602 in the peptidyl transferase center of 23s-like rrna within ribosome-trna complexesThe antitumor antibiotic sparsomycin is a universal and potent inhibitor of peptide bond formation and selectively acts on several human tumors....

santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov

Publications scientifiques

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Synthesis and biological evaluation of sparsomycin analogues... The structure of the crystalline antibiotic, named sparsomycin, remained elusive until 1970, when Wiley and MacKellar reported results of spectroscopic and degradation studies which elucidated the structure....

général - core.ac.uk - PDF: scholarscompass.vcu.edu

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Interaction of the antibiotic sparsomycin with the ribosome.Phenol-alanine-sparsomycin, a derivative of sparsomycin carrying a p-hydroxy-benzyl function easily labeled by iodination, has been used to study the interaction of this drug with the ribosome....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Characterization of sparsomycin resistance in streptomyces sparsogenesThe antitumor antibiotic sparsomycin, produced by Streptomyces sparsogenes, is a universal translation inhibitor that blocks the peptide bond formation in ribosomes from all species....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Synergistic effect of pactamycin and sparsomycin on mycoplasma-induced lethal toxicity of micePactamycin and sparsomycin, antitumor drugs which act synergistically with endotoxins, also potentiate the lethal toxicity of mice by Mycoplasma fermentans, strain K10....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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