Disregarding one of them will typically lead to sub-optimization.

The first one is the sub-optimal cold chain even before the typhoon.

It is therefore a deliberate sub-optimization which we have sadly inherited on our computers due to force of habit.

A lack of omega-3 at this stage of development results in sub-optimal visual and cognitive function.

Use techniques such as co-location and cross-functional communication channels to reduce siloing and suboptimization.

So there needs to be some kind of sync between the product owners so that we build things in a sensible order, and avoid sub optimization.

Selecting whatever work seems most important at the start of each iteration can be sub-optimizing in some cases.