The nucleic acid probe hybridizes with the specific nucleic acid sequence but not with other nucleic acid sequences in the population.

Method of nucleic acid hybridization for detecting the presence of a specific nucleic acid sequence in a population of different nucleic acid sequences using a nucleic acid probe.

Said oligonucleotide also consists of stem sections (14, 16) that are arranged on both ends of the loop section and can hybridise with each other for closing the oligonucleotide (10) in such a way that said oligonucleotide forms a loop.

The invention relates to an oligonucleotide (10) which serves as nucleic acid probe and consists of a loop section (18) that is provided with a loop sequence being complementary to a target sequence of the nucleic acid molecule.

According to the invention, a nucleic acid probe which does not require the preparation of a nucleic acid probe with an expensive fluorescence label for each target nucleic acid can be provided.

The present invention also provides a kit for measuring the modified nucleic acid base, the kit comprising a heterogeneous nucleic acid probe, and an antibody to the modified nucleic acid base.

A nucleic acid probe with a substantially neutral net charge is used for detecting the target nucleic acid.

More specifically, it relates to methods and compositions for promoting the hybridization of a nucleic acid probe with a target nucleic acid sequence which is not perfectly matched to the probe.

PNA is a very stable molecule with very high affinity for nucleic acid allowing a PNA probe to be shorter than conventional nucleic acid probes.

This invention provides an isolated nucleic acid molecule encoding human myeloblastin, a nucleic acid probe for detecting myeloblastin, and an antisense oligodeoxynucleotide complementary to myeloblastin mRNA.

Also, a nucleic acid probe is complementary to a portion of a human mutant p107 gene.

The nucleic acid probe comprises a probe polynucleotide, a charged hapten label, and a binding moiety.

This invention also provides a nucleic acid probe capable of specifically hybridizing with a sequence included within the sequence of a nucleic acid molecule encoding a dorsalin-1.

The invention relates to a method for detecting microorganisms in a sample by means of a nucleic acid probe.

In particular disclosed embodiments, the gene locus probe may be a nucleic acid probe that includes or consists of a nucleic acid sequence set forth as any one of SEQ ID NOs: 1-50.