Functional interplay between the b-box 2 and the b30.2(spry) domains of trim5α AbstractThe retroviral restriction factors, TRIM5α and TRIMCyp, consist of RING and B-box 2 domains separated by a coiled coil from carboxy-terminal domains....
A human b-box-binding protein downregulated in adenovirus 5-transformed human cells ... tRNA genes, adenovirus VA1 RNA gene, human retroposons of the Alu family) contain a conserved sequence element, B-box, interacting with basal transcription factor TFIIIC2 which initiates assembly of the full transcription complex on the genes and which represents the major determinant of...
The trim5α b-box 2 domain promotes cooperative binding to the retroviral capsid by mediating higher-order self-association▿... TRIM5α consists of RING, B-box 2, coiled-coil, and B30.2(SPRY)...
Ring/b-box of trim38 is critical for trif degradation.... 293T cells were transfected with plasmids expressing Myc-tagged full-length or RING/B-box domain deleted (ΔRING/B-box) TRIM38, Flag-TRIF, and HA-ubiquitin plasmids....
