Each of the antigen polypeptides is a wild-type antigen protein of Plasmodium or a derivative of the wild-type antigen protein, and each of the antigen polypeptides may be the same, or different.

If the target protein or peptide is an antigen protein or an antigen peptide, the transformed Bifidobacterium is useful as an oral vaccine.

The specific antigen protein of the tumor cells can be WT-1.

The occurrence of cancer in a living body can be also detected by measuring an antigenic protein for the antibody or mRNA encoding the antigenic protein.

The present invention relates to an isolated antigenic protein of Helicobacter pylori.

The invention relates to an antigenic protein derived from Streptococcus pneumoniae.

By using this method, an antigen protein easily undergoing antigen-presentation can be selected from among a plural number of proteins.

Bacteria according to the present invention may also be transformed with DNA encoding an antigenic protein.

Preferred antigenic protein fragment sequences are also described.

Further, it is found out that the amount of a taken up antigen protein and the amount of the antigen protein polyubiquitinated by a dendritic cell positively correlate to the antigen-presentation level.

This antigenic protein, termed ASE-1 has an approximate molecular mass of 55 kDa.

A novel antigenic protein derived from the outer membrane of H.influenzae is provided.

Owing to the function of the folding factor, the antigen protein contained in the fused protein can be obtained as a soluble protein having a correct stereostructure.

with the presence of the antigenic but sub-threshold protein;

Once inside, the nanoparticle can protect this antigenic protein so it won't be degraded.