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pravadoline

santé / chimie - iate.europa.eu
Further evidence for the presence of cannabinoid cb1 receptors in guinea-pig small intestine.... Electrically-evoked contractions of the myenteric plexus-longitudinal muscle preparation were also inhibited by AM 630 (6-iodo-pravadoline) and by WIN 55,212-2 (IC50 = 1923.0...
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Combined antiproliferative effects of the aminoalkylindole win55,212-2 and radiation in breast cancer cells... Interestingly, while other aminoalkylindoles, pravadoline and JWH-015, enhanced the antiproliferative effects of radiation, this was not the case for other synthetic cannabinoids (i.e.,...
Water-soluble hypervalent iodine(iii) having an i–nbond. a reagent for the synthesis of indoles...CH3CN.Notably, using this new method as the key step, not only two drugmolecules, indometacin and zidometacin, but also another bioactivemolecule, pravadoline, were synthesized
Oo223565/9o/2553.123o$o3.oo/o the journal op pharmacology and experimental therapeutics copyright c 1990 by the american society for pharmacology and experimental therapeutics pravadoline: profile in isolated tissue preparationsPravadoline is a novel cyclooxygenase-inhibiting analgesic with a preclinical profile of activity in vivo clearly distinct from that of other cyclooxygenase inhibitors....


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