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porfiromycine

porfiromycin

général / santé / chimie - eur-lex.europa.eu iate.europa.eu
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Deficient activation by a human cell strain leads to mitomycin resistance under aerobic but not hypoxic conditions.Two non-transformed human skin fibroblast strains, GM38 and 3437T, were found to be more sensitive to the bioreductive alkylating agents mitomycin C (MMC) and porfiromycin (PM) under hypoxic compared to aerobic conditions....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Plasma mitomycin c concentrations determined by hplc coupled to solid-phase extraction... The use of porfiromycin as internal standard provided a method with good within-day precision (CV 6.0%...
 PDF: air.unimi.it
Mutation research 488 (2001) 25–37 genotoxicity of streptonigrin: a review... This compound is a member of a group of antitumor agents which possess the aminoquinone moiety and that includes also mitomycin C, porfiromycin, actinomycin, rifamycin and geldanamycin....
 PDF: citeseerx.ist.psu.edu
Differential toxicity of mitomycin c and porfiromycin to aerobic and hypoxic chinese hamster ovary cells overexpressing human nadph:cytochrome c (p-450) reductase.... In contrast, porfiromycin was considerably less cytotoxic to wild-type parental cells than was mitomycin C in air and markedly more cytotoxic under hypoxia....
 PDF: www.pubmedcentral.nih.gov


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