When administered to the human body directly, the ribozyme polyribonucleotide can incise the target polyribonucleotide in vivo efficiently, thus being utilizable as a carcinostatic agent, anti-AIDS drug, and so forth.
The invention relates to a polyribonucleotide, a cosmetic and pharmaceutical compound that has the polyribonucleotide and a medicinal product that has the polyribonucleotide and the compound.
The invention provides a polyribonucleotide having a thermodynamically stable looped structure and a ribozyme activity, a DNA which codes for the same, and so forth.
The polyribonucleotide is exemplified by the one with structure (b).
The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules.
Further provided are a polyribonucleotide for encoding the fusion protein, a method for preparing the fusion protein, and an application of the fusion protein in the preparation of an antiviral drug.
Inasmuch as it seems to act directly at the level of the DNA, it seemed logical to assume that it could be a polyribonucleotide whose association with a DNA sequence would take place by means of specific pairing.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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