The invention relates to a new fixed dose combination of benazepril with pimobendan.
The invention relates to novel liquid preparation comprising a substituted benzimidazol, preferably pimobendan as pharmaceutically active compound.
The interim analysis did not raise any concern over the safety of pimobendan administration.
Pimobendan may also be used in combination with a diuretic, e.g. furosemide.
Administration of pimobendan should take place approximately one hour before feeding.
The compound is oxidatively demethylated to its major active metabolite (UD-CG 212).
The compound is demethylated by oxidation to the major active metabolite (UD-CG212).
The compound is demethylated by oxidation to the major active metabolite (UD-CG212).
Metabolism The compound is oxidatively demethylated to its major active metabolite (UD-CG 212).
Pimobendan, a benzimadazole-pyridazinone derivative has a positively inotropic action and possesses pronounced vasodilator properties.
The volume of distribution is 2.6 l/kg, indicating that pimobendan is distributed readily into the tissues.
Distribution: After intravenous administration the volume of distribution is 2.6 l/kg indicating that pimobendan is distributed readily into the tissues.
Distribution: The volume of distribution is 2.6 l/kg, indicating that pimobendan is distributed readily into the tissues.
Since simultaneous or previous food intake reduces the bioavailability, pimobendan should be administered about 1 hour before feeding.
Since albendazole is processed largely by the liver, it should not be used in dogs who have any type of liver condition.
Pimobendan, a benzimidazole-pyridazinone derivative, is a non-sympathomimetic, non-glycoside inotropic substance with potent vasodilatative properties.
Distribution The volume of distribution is 2.6 l/kg, indicating that pimobendan is distributed readily into the tissues.
Since pimobendan is metabolised mainly via the liver, it should not be used in dogs with severe impairment of liver function.
Distribution The volume of distribution is 2.6 l/kg, indicating that pimobendan is distributed readily into the tissues.
Distribution: The volume of distribution is 2.6 l/kg, indicating that pimobendan is distributed readily into the tissues.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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