Preferably, the paroxetine hydrochloride is paroxetine hydrochloride hemihydrate.
Also described are methods for preparing paroxetine carbonate, paroxetine phosphate, paroxetine sulfate, and analogous salts thereof.
The invention relates to a new paroxetine salt, that is the (-)-paroxetine-(+)-L-monotartarate hemihydrate, which is a new antidepressant compound.
In this process paroxetine maleate in solution is directly converted to solid paroxetine hydrochloride, avoiding formation of paroxetine free base and subsequent re-acidifying with hydrogen chloride.
Pharmaceutical formulations of paroxetine are provided in which the paroxetine is in solution in a solid, semi-solid or liquid carrier.
Paroxetine intermediates such as PMA, paroxetine, and pharmaceutically acceptable salts thereof substantially free of alkoxy impurities also form part of the present invention.
Pharmaceutical compositions comprising paroxetine methanesulfonate are described.
Also provided are processes for the preparation of paroxetine.
Compound (2) is used in the presentation of paroxetine.
Paroxetine prepared by the above processes can be neutralized with hydrogen chloride and crystallized as paroxetine hydrochloride anhydrous, hemilhydrate or as a solvate of isopropanol.
Active ingredient : Paroxetine Manufactured by : Various
Metabolism does not impair the ability of paroxetine to selectively inhibit the reuptake of serotonin.
The present invention relates to stable pharmaceutical compositions of paroxetine and process for preparation thereof.
Each film-coated tablet contains 10 mg/20 mg/30 mg paroxetine (as paroxetine hydrochloride hemihydrate).
Side effects of paroxetine: confusion, hallucination
The invention relates to solid or semi-solid preparations of paroxetine or one of the physiologically acceptable salts thereof in the form of a molecular-disperse distribution of paroxetine in a pharmaceutically acceptable matrix material.
There is described a process for the preparation of paroxetine acetate and analogues thereof.
The resultant (-) trans piperidine carbinol of structure (1) may be coupled with sesamol, then deprotected, to give paroxetine (2), with optional formation of a pharmaceutically acceptable salt of paroxetine.
Antidepressants, such as fluoxetine or paroxetine.
How effective is dapoxetine for premature ejaculation?
Metabolism does not impair the ability of paroxetine to selectively inhibit the reuptake of serotonin.
The paroxetine salts may be formulated for the treatment of medical disorders as described.
The hyponatraemia generally reverses on discontinuation of paroxetine.
Antidepressants such as paroxetine, fluoxetine, tricyclic antidepressants
Disclosed herein is a paroxetine cholate or cholic acid derivative salt and a composition comprising paroxetine and cholic acid or a derivative thereof.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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