The preferred ORFs, to be expressed, include a non-phosphorylatable retinoblastoma ORF, a dominant negative mutant of a human RAS ORF and a Herpes thymidine kinase ORF.
Formula (I), wherein R1 is selected from C1-C3-alkyl, C1-C3-haloalkyl, C1-C3-alkoxy and C1-C3-haloalkoxy; R2 is selected from hydrogen and C1-C3-alkyl; and R3 is selected from C1-C3-alkyl, C1-C3-haloalkyl, C1-C3-alkoxy and C1-C3-haloalkoxy.
Sequencing of an 10-kb region identified 9 ORFs and an additional partial ORF.
ORF-theme from 15.12.2008, at 21:10, ORF 2 (repeat, 16.12.2008, 9:30 am) © ORF:
Fly from Baltimore (BWI) to Norfolk (ORF) BWI - ORF
Fly from Reagan Washington (DCA) to Norfolk (ORF) DCA - ORF
Fly from Philadelphia (PHL) to Norfolk (ORF) PHL - ORF
Balance has to be read as follows: balance = 100 – C3 ≤ C3 ≥ C4.
The amino acid sequence of the carboxyterminal end of KSHV orf 65 is given below: Sequence 1: Amino acids 86 - 170 of KSHV orf 65.
The present invention relates to recombinant orf virus, and use and methods involving such recombinant orf virus in the treatment of hyperproliferative disorders.
In general formula (1), R5 is a hydrogen atom, hydroxyl, C1-3 alkyl, C1-3 alkoxy, a C1-3 carboxylic acid group, or a C1-3 amido group.
Advantageously, such engineering allows the orf virus to better replicate in human cells, while still maintaining the orf virus' unique immune stimulatory profile.
By introduction of a mutation in the ORF a mutated ORF is produced.
The ninth ORF was essential for biosynthesis of the avermectin aglycones.
Flights arriving in Norfolk Norfolk International Airport ORF
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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