The present invention relates to a bispecific antibody molecule, as well as a method for producing the same, its use and a nucleic acid molecule encoding the bispecific antibody molecule.
The invention further relates to pharmaceutical compositions comprising said bispecific single chain antibody molecule and medical uses of said bispecific single chain antibody molecule.
The invention relates to an ahumanized antibody molecule having specificity for antigenic determinants of IL-1β, andwhich is made with CDRs from the murine antibody IC8 that are grafted into human frameworks.
Described are methods of inhibiting angiogenesis, the methods comprising the simultaneous, sequential or separate administration of (i) an anti- Cathepsin S antibody molecule, and (ii) an anti-VEGF antibody molecule.
Moreover, qualities of an antibody molecule can be easily evaluated thereby.
Therefore, the antibody’s two light chains are identical.
The affibody molecule binds with high affinity to select receptors, which are over-expressed in certain cancers.
The electrochemiluminescence signal generated by each anti-analyte molecule (i.e., each analyte molecule) is much greater than with the conventional method.
A second bispecific antibody molecule is bivalent for CD-28 and at least monovalent for the tumour antigen.
Thus, an antibody molecule can be analyzed in a few steps at a high reproducibility.
The invention also provides nucleic acids encoding said bispecific single chain antibody molecule as well as vectors and host cells and a process for its production.
The invention also provides nucleic acids encoding said bispecific single chain antibody molecule as well as vectors and host cells and a process for its production.
The invention also provides nucleic acids encoding said bispecific single chain antibody molecule as well as vectors and host cells and a process for its production.
The invention further relates to pharmaceutical compositions comprising said bispecific single chain antibody molecule and medical uses of said bispecific single chain antibody molecule.
The invention further relates to pharmaceutical compositions comprising said bispecific single chain antibody molecule and medical uses of said bispecific single chain antibody molecule.
The invention further relates to pharmaceutical compositions comprising said bispecific single chain antibody molecule and medical uses of said bispecific single chain antibody molecule.
More specifically, a pharmaceutical and a diagnostic composition comprising said antibody molecule and antibody mixtures are provided which is/are capable of specifically recognizing the β-A4 peptide/Aβ4.
Also disclosed is a method for producing an antibody, which comprises collecting the functional antibody molecule from a cocoon of the silkworm.
Means to target the activation of prodrugs to specific cells by linking the enzyme to an antibody molecule.
The invention in particular provides an antibody molecule that is capable of mediating target cell restricted activation of immune cells.
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