The role of pparβ/δ in melanoma metastasis.... This observation was further supported by an increased tumour burden in the lungs of Pparβ/δ <sup>-/-</sup> mice as demonstrated in the same animal model.These...
Sequential treatment with cytarabine and decitabine has an increased anti-leukemia effect compared to cytarabine alone in xenograft models of childhood acute myeloid leukemia... Sequential treatment with decitabine and cytarabine was found to be more effective in reducing tumour burden than treatment with cytarabine alone suggesting that the sequential delivery of these agents may a have real clinical advantage in the treatment of paediatric AML....
Arq-197, a small-molecule inhibitor of c-met, reduces tumour burden and prevents myeloma-induced bone disease in vivo... In vivo ARQ-197 treatment of JJN3 tumour-bearing mice resulted in a significant reduction in tumour burden, tumour cell proliferation, bone lesion number, trabecular bone loss and prevented significant decreases in the bone formation rate on the cortico-endosteal bone...
Arq-197, a small-molecule inhibitor of c-met, reduces tumour burden and prevents myeloma-induced bone disease in vivo.... In vivo ARQ-197 treatment of JJN3 tumour-bearing mice resulted in a significant reduction in tumour burden, tumour cell proliferation, bone lesion number, trabecular bone loss and prevented significant decreases in the bone formation rate on the cortico-endosteal bone...
