The second component is a cytotoxic pro-drug convertible by said enzymatically active portion to the cytotoxic drug.
Compositions of matter comprising a substituted cyclodextrin and cytotoxic compound, especially cytotoxic drugs such as antibiotic, anti-fungal and anti-neoplastic drugs are claimed.
The chemotherapeutic agent is preferably a cytotoxic drug, or a drug having both cytotoxic and antiestrogenic mechanisms of action.
The first component comprises a target cell-specific portion and an enzymatically active portion capable of converting a cytotoxic pro-drug into a cytotoxic drug.
The cytotoxic drug can be melphalan or a derivative or analogue thereof.
Levact is a medicine which is used for the treatment of certain types of cancer (cytotoxic medicine).
More than three quarters (78 %) of the participants had been exposed to the drug.
Cytotoxic drug derivative/antibody conjugates, compositions comprising the conjugates and uses of the conjugates are also described.
The active substance in Caelyx, doxorubicin hydrochloride, is a cytotoxic medicine that belongs to the group ‘anthracyclines’.
The pharmaceutical preparations according to yet a further embodiment may be used for increasing the efficacy of a cytotoxic drug towards target cells, the target cells, being, for example, cancer cells.
X70-X71 Procurement of drugs for chemotherapy for neoplasm Bands 1–10 (depending on the cytotoxic drug used)
The use of the second component reduces the extent to which the cytoxic drug is released from the third component in regions of a patients body remote from the target tumour.
This rebound can be minimized, in animals, by administering a cytotoxic drug that blocks the cells that make new antibodies.
The active substance in Ecansya, capecitabine, is a cytotoxic medicine (a medicine that kills cells that are dividing, such as cancer cells) that belongs to the group ‘antimetabolites’.
The active substance in Xeloda, capecitabine, is a cytotoxic medicine (a medicine that kills cells that are dividing, such as cancer cells) that belongs to the group ‘anti-metabolites’.
The active substance in Capecitabine Accord, capecitabine, is a cytotoxic medicine (a medicine that kills cells that are dividing, such as cancer cells) that belongs to the group ‘anti-metabolites’.
The active substance in Ecansya, capecitabine, is a cytotoxic medicine (a medicine that kills cells that are dividing, such as cancer cells) that belongs to the group ‘anti-metabolites’.
The main active substance in Teysuno, tegafur, is a cytotoxic medicine (a medicine that kills cells that are dividing, such as cancer cells) that belongs to the ?anti-metabolites? group.
The active substance in Capecitabine Accord, capecitabine, is a cytotoxic medicine (a medicine that kills cells that are dividing, such as cancer cells) that belongs to the group ‘anti-metabolites’.
The active substance in Capecitabine Medac, capecitabine, is a cytotoxic medicine (a medicine that kills cells that are dividing, such as cancer cells) that belongs to the group ‘anti-metabolites’.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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