The regulatory T cells can be human T cells.

Provided are methods of modulating activity of regulatory T cells, CD4+ T cells, and CD8+ T cells.

A mixed lymphocyte response is generated by incubating the peripheral blood lymphocytes in the presence of allogeneic lymphocytes.

Disclosed herein are methods and compositions for expanding T-regulatory cells ("Treg" cells), resulting in "conditioned Treg cells."

The present invention relates to inhibiting proliferation and inducing apoptosis in activated lymphocytes, including T cells and B cells.

The technology is directed to methods for the production of selected populations of lymphocytes, such as T cells and NK cells.

Exemplary T-cells include CD4+ T-cells and CD8+ T-cells and exemplary B-cells are ASC.

The activity of the anti-idiotypic T cells of interest is related to the ability of these T cells to recognize anti-p277 T cells.

Methods for the ex vivo generation of cells of the innate (NKT cells and NK cells) and adaptive (T cells) immune systems for use in adoptive cell transfer (ACT) are provided.

The immunosuppressive property of the compound is targeted in particular against the lymphocytes, CD4+ T cells, CD8+ T cells and B cells and in the production of IL-4 and IFN-Ϝ and antibodies.

methods are provided to specifically modulate the trafficking of systemic memory T cells, particularly CD4+ T cells, without affecting naive T cells or intestinal memory T cells.

The memory CD8+ T cells may include one or both of central and effector memory T cells, usually both.

The invention provides isolated regulatory T cells and methods of obtaining regulatory T cells.

where lymphocytes are used, whether whole blood or separated lymphocytes are exposed

By employing lymphocytes or other antibodies or cytotoxic agents, inflammatory disorders mediated by cutaneous lymphocytes or other T-cells or skin associated T-cell malignancies may be treated.