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hypothèse de Lyon

Lyon hypothesis

sciences naturelles et appliquées / santé - acta.es iate.europa.eu

Hypothèse de Lyon (Anglais : Lyon hypothesis) Hypothèse suggérée par Mary Lyon sur l'inactivation d'un des deux chromosomes X chez la femme.

Lyon Hypothesis: Idea proposed by Mary Lyon that mammalian females inactivate one or the other X-chromosome during ea

général - CCMatrix (Wikipedia + CommonCrawl)

hypothèse de Lyon

Publications scientifiques

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Hurler's syndrome: a genetic study of clones in cell culture with particular reference to the lyon hypothesis*':~... The Lyon hypothesis (5) postulates that random inactivation of one of the two X chromosomes in normal mammalian female cells occurs early in embryogenesis....

général - core.ac.uk - PDF: citeseerx.ist.psu.edu

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Hurler's syndrome: a genetic study of clones in cell culture with particular reference to the lyon hypothesis... The appearance of two distinct cell populations in clones derived from females heterozygous for the X-linked recessive form of Hurler's syndrome provides evidence in favor of the Lyon hypothesis

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Menkes x linked disease: two clonal cell populations in heterozygotes.... For each obligate heterozygote, two clonal cell populations were observed, one with a Menkes phenotype and one with a normal phenotype, as predicted by the Lyon hypothesis....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Detection of hunter heterozygotes by enzymatic analysis of hair roots.... The results are consistent with the origin of hair roots from a small number of progenitor cells which obey the Lyon hypothesis....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Expression of two x-linked genes in human hair follicles of double heterozygotes... These data directly demonstrate one of the predictions of the Lyon hypothesis that for two X-linked loci, those genes in cis position are turned on or off in a cell and its clone, while in trans only one gene or the other is expressed

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov