The trans-acting regulatory genes of HTLV-I, HTLV-II, HTLV-III and BLV are disclosed.
Molecular clones of HTLV-III/LAV.
The tat-3 gene of HTLV-III is expressed at high levels in E. coli and is reactive with antibodies induced in response to infection by HTLV-III and can induce production of antibodies which are reactive with HTLV-III.
The invention also provides a method for identifying substances which inhibit HTLV-III reverse transcriptase and a method for treating an HTLV-III virus-related disease.
LAV and HTLV-III were later acknowledged to be the same.
LAV and HTLV-3 were shown to be the same virus in 1985.
It was a new retrovirus called HTLV-III, (later re-named HIV).
Cells infected with HTLV-III yield a protein (p27) having an apparent molecular weight of about 27,000 daltons.
Method for detecting antibodies to human T-cell leukemia virus Type III (HTLV-III), the virus associated with Acquired Immune Deficiency Syndrome (AIDS).
Molecular cloning of HTLV-III, the adult leukemia and acquired immune deficiency syndrome (AIDS) virus.
The viral infectivity is then assayed using a monoclonal antibody specific for HTLV-III p24 in an immune fluorescent assay.
Method of measuring natural human antibodies in sera which will neutralize HTLV-III infection in an in vitro assay.
The probe detects HTLV-III in primary, uncultured tissue samples, is highly sensitive, and is relatively fast acting.
Stability and inactivation of HTLV-III/LAV under clinical and laboratory environments.
Stability and inactivation of HTLV-III/LAV under clinical and laboratory environ- ments.
Stability and inactivation of HTLV III/LAV under clinical and laboratory environments.
Stability and inactivation of HTLV-III/LAV under clinical and laboratory environments".
Subacute encephalomyelitis of AIDS and its relation to HTVL-III infection.
LAV and HTLV-III are the same virus, named in 1986 human immunodeficiency virus, or HIV.
Doctors at the US National Cancer Institute identify a virus – human T- lymphotropic virus type III (HTLV-III) – they believe causes AIDS.
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