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The function of lgr5+ cells in the gastric antrum does not require fzd7 or myc in vivo... Wnt signalling is a critical niche component for gastrointestinal stem cells and we have previously shown that the Wnt receptor, Frizzled-7 (Fzd7), is required for gastric homeostasis and the function of Lgr5+ intestinal stem cells....

santé - core.ac.uk - PDF: orca.cf.ac.uk

Publications scientifiques

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From inflammation to gastric cancer – the importance of hedgehog/gli signaling in helicobacter pylori-induced chronic inflammatory and neoplastic diseases... pylori-associated Hedgehog/GLI signaling in gastric homeostasis, malignant development and the modulation of the gastric tumor microenvironment

général - core.ac.uk - PDF: doaj.org

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Gastric cancer and hedgehog signaling pathway: emerging new paradigms... It has now become clear that hedgehog signaling is of pivotal importance in gastric homeostasis....

général - core.ac.uk - PDF: www.loc.gov

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Fibroblast growth factors in gastrointestinal development, homeostasis and injury...proliferation.In order to study the requirement of Fgfr2b in gastric homeostasis, wecharacterised two stomach-specific minimal promoters for trefoil factor 1(Tff1) and H+K+-ATPase (Atp4b) to generate two inducible Crerecombinase (CreERT2)...

général - core.ac.uk - PDF: spiral.imperial.ac.uk:8443

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Selective cyclo-oxygenase-2 inhibitors and their influence on the protective effect of a mild irritant in the rat stomach... Prostaglandis generated by a constitutive COX-2 could thus contribute to physiological functions involved in gastric homeostasis, although at present a non-COX-2-related mechanism underlying the effect of the selective COX-2 inhibitors tested on mild irritant-induced protection cannot...

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov