Dictionnaire français - anglais

HMG

sciences naturelles et appliquées - iate.europa.eu
Étude de la variante d'histone h2a.z de saccharomyces cerevisiae dans un système de transcription in vitro sur une matrice chromatinienne reconstituée... Bien que plusieurs autres protéines entrent dans sa composition, comme des protéines"high mobility group" (HMG), l'agencement ADN-histones est à la base de la chromatine....
général - core.ac.uk -
Rac-2-[2-(4-fluoro­phen­yl)-2-oxo-1-phenyl­eth­yl]-4-methyl-3-oxo-n-phenyl­penta­namideThe title compound, C26H24FNO3, is a critical inter­mediate of a selective and competitive inhibitor of the enzyme 3-hy­droxy-3-methyl­glutaryl-coenzyme A (HMG–CoA) reductase....
Rac-2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-n-phenylpentanamideThe title compound, C26H24FNO3, is a critical intermediate of a selective and competitive inhibitor of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG–CoA) reductase....
 PDF: doaj.org
HMG
chimie - iate.europa.eu
La synthèse du cholestérol se fait dans le cytoplasme des cellules (surtout l’intestin et le foie) à partir de l’hydroxy-méthyl-glutaryl-CoA (HMG-CoA).

Cholesterol is synthesized in the cytoplasm of cells (especially the intestine and liver) from hydroxy-methylglutaryl-CoA (HMG-CoA).

général - CCMatrix (Wikipedia + CommonCrawl)
Rho-gtpase and atherosclerosis: pleiotropic effects of statins3-Hydroxy-methylglutaryl-coenzyme A (HMG-CoA) reduc-tase inhibitors or statins are a class of medications with potent effects on reducing serum cholesterol level, and currently ...
général - core.ac.uk - PDF: jaha.ahajournals.org
Human t cell receptor �� cells recognize endogenous mevalonate metabolites in tumor cells... In tumor cells, blockade of hydroxy-methylglutaryl-CoA reductase (HMGR), the rate limiting enzyme of the mevalonate pathway, prevents both accumulation of mevalonate metabolites and recognition by TCR-� ...
Educational objective: readers will assess the current evidence for using coenzyme q10 supplements...and statin-induced myalgia? Some small clinical trials seem to show that coenzyme Q10 supplements can be used to lower blood pressure and to treat or prevent myalgia caused by hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins)....
Expression of defense-related genes in citrus leaves infected with δxacpnp and xcc (xccwt).... MKK4, MAP kinase kinase 4; PRXa, peroxidorexin; Rboh, NADPH oxidase; GST, glutathione-S-transferase; PAL, phenylalanine ammonia lyase; HMGR, 3-hydroxy-methylglutaryl CoA reductase; Lox2, lipoxygenase 2....
Hyperexpression of low-density lipoprotein receptors and hydroxy-methylglutaryl-coenzyme a-reductase in... In this study, the expression of two main genes correlated to cholesterol metabolism—namely, the low-density lipoprotein receptor (LDL-R) gene and the hydroxy-methylglutaryl-coenzyme A-reductase (HMG-CoA-R) gene—were investigated in primary pterygium, pinguecula, and normal conjunctiva....
HMG
chimie - iate.europa.eu
La réductase HMG-CoA catalyse la conversion du HMG-CoA en mevalonate.

HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate.

général - CCMatrix (Wikipedia + CommonCrawl)
Ces médicaments agissent en inhibant l'hydroxyméthylglutaryl (HMG) CoA réductase (HMG CoA reductase).

These medicines act by inhibiting hydroxymethylglutaryl (HMG) CoA reductase (HMG CoA reductase).

général - CCMatrix (Wikipedia + CommonCrawl)
La réductase HMG-CoA catalyse la conversion du HMG-CoA en mevalonate.

The HMG-CoA reductase enzyme catalyzes the conversions of HMG- CoA to mevalonate.

général - CCMatrix (Wikipedia + CommonCrawl)
La réductase HMG-CoA catalyse la conversion du HMG-CoA en mevalonate.

HMG-CoA reductase that catalyzes the conversion of HMG-CoA into mevalonate.

général - CCMatrix (Wikipedia + CommonCrawl)
Les compositions comprennent une boîte HMG A de vertébré et une préparation d'anticorps qui se lie de manière spécifique à une boîte HMG B de vertébré.

The compositions comprise a vertebrate HMG A box, and an antibody preparation that specifically binds to a vertebrate HMG B box.

santé - wipo.int
The risk of cancer in statin users : a clinical and genetic approach
Les statines, inhibiteurs de la 3-hydroxy-3-methylglutaryl-coenzyme (HMG-CoA) réductase sont efficaces et largement utilisées dans le traitement des troubles lipidiques, surtout pour l’hypercholestérolémie....
...Statins, 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, are efficient and widely used drugs in the treatment of lipid disorders, especially hypercholesterolemia....
général - core.ac.uk -
Statines et artérites à cellules géantes : approche pharmaco-épidémiologique
Nous proposons une revue de la littérature approfondie sur la pharmacologie des inhibiteurs de l'HMG-CoA réductase et les résultats de nos études sur leur utilisation dans l'artérite à cellules géantes....
...We propose a comprehensive review on HMG-CoA reductase inhibitors pharmacology and results of our studies on their use in giant cell arteritis....
général - core.ac.uk - PDF: core.ac.uk

Publications scientifiques

A high-mobility-group protein and its cdnas from drosophila melanogaster.We have identified, purified, and characterized a high-mobility-group (HMG) protein and its cDNAs from Drosophila melanogaster....
chimie - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Selective decrease in low-mr hmg proteins hmg i and hmg y during differentiation of mouse teratocarcinoma cells AbstractWe have studied the presence of high-mobility-group (HMG) chromatin proteins in undifferentiated F9 mouse teratocarcinoma cells and F9 cells, which were induced to differentiate by treatment with retinoic acid and dibutyryl-cAMP...
général - core.ac.uk -
Hmg-box sequences from microbats homologous to the human sox30 hmg-box ∗SOX genes are a family of genes that encode for proteins which are characterised by the presence of a HMGdomain related to that of the mammalian sex-determining gene (SRY)....
général - core.ac.uk - PDF: citeseerx.ist.psu.edu
Neither hmg-14a nor hmg-17 gene function is required for growth of chicken dt40 cells or maintenance of dnasei-hypersensitive sites.HMG-14 and HMG-17 form a family of ubiquitous non-histone chromosomal proteins and have been reported to bind preferentially to regions of active chromatin structure....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Competition between hmg-i(y), hmg-1 and histone h1 on four-way junction dnaHigh mobility group proteins HMG-I(Y) and HMG-1, as well as histone H1, all share the common property of binding to four-way junction DNA (4H), a synthetic substrate commonly used to study proteins involved...
général - core.ac.uk - PDF: nar.oxfordjournals.org

Traductions en contexte français - anglais

Lovastatin est un inhibiteur spécifique de HMG-CoA reductase, l'enzyme qui catalyse la conversion de HMG-CoA à mevalonate.

Simvastatin is a specific inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate.

général - CCMatrix (Wikipedia + CommonCrawl)
L'invention concerne l'utilisation de molécules de liaison de domaine HMG et de molécules présentant une homologie de séquence avec le domaine HMG dans la préparation d'agents thérapeutiques destinés au traitement de maladies vasculaires.

The use of HMG box-binding molecules and molecules having sequence homology with HMG box for the preparation of therapeutic agents for the treatment of vascular diseases is described.

chimie - wipo.int
La forme posologique assure une stabilité chimique améliorée à l'inhibiteur de HMG-CoA réductase.

The dosage form provides improved chemical stability of the HMG-CoA reductase inhibitor.

santé - wipo.int
La HMG n’est disponible que sous forme injectable.

However, hGH is only bioavailable in the injectable form.

général - CCMatrix (Wikipedia + CommonCrawl)
La présente invention concerne un procédé de préparation d’un inhibiteur de la HMG-CoA réductase.

The present invention is in relation to a process for preparation of HMG-CoA reductase inhibitor.

chimie - wipo.int
Quelques femmes souffrent des effets secondaires des hMG.

Some women do suffer from side effects of hMG’s.

général - CCMatrix (Wikipedia + CommonCrawl)
En outre, HMG augmente la production d’hormone lutéinisante.

In addition, HMG increases luteinizing hormone production.

général - CCMatrix (Wikipedia + CommonCrawl)
Le composé selon la présente invention a un effet inhibiteur sur la HMG-CoA réductase.

The compound of the present invention has an inhibitive effect on HMG-CoA reductase.

chimie - wipo.int
Ceux-ci s'appellent les gonadotrophins ménopausiques humains (hMG).

These are called human menopausal gonadotrophins (hMG).

général - CCMatrix (Wikipedia + CommonCrawl)
Les médicaments sont appelés Menopur et HMG Lepori.

These medications are known as Menopur and hMG-lepori.

général - CCMatrix (Wikipedia + CommonCrawl)
Les produits obtenus sont indiqués comme des inhibiteurs de HMG-CoA reductase ou leurs intermédiaires.

The products obtained are suitable as HMG-CoA reductase inhibitors or intermediates thereof.

sciences naturelles et appliquées - wipo.int
L'invention concerne un procédé de production de statines, connues comme inhibiteurs de réductase HMG-CoA.

The invention relates to a method for producing statins known as HMG-CoA reductase inhibitors.

chimie - wipo.int
Ledit hypolypidémiant est sélectionné à partir de l'inhibiteur de réductase de la HMG CoA-réductase.

The lipid lowering agent is selected from HMG Co-enzyme-A reductase inhibitor.

agriculture, sylviculture et pêche - wipo.int
L'inhibiteur de réductase HMG-CoA est de préférence administré sur le site par un excipient.

The HMG-CoA reductase inhibitor is preferably delivered to the site by a carrier.

santé - wipo.int
Dans un mode de réalisation préféré, l'inhibiteur de la HMG-CoA réductase est la lovastatine.

In a preferred embodiment, the HMG-CoA reductase inhibitor is lovastatin.

santé - wipo.int


1 milliard de traductions classées par domaine d'activité en 28 langues