In fact, only a microscope examination (anatomopathological examination) can confirm the diagnosis.

Neuropathological findings most commonly involve diffuse, multifocal destruction of the white matter and subcortical structures.

Results: The diagnosis of PMC was suspected in the preoperative period in 15% of the patients, and was confirmed intraoperatively by the pathologist in 42% of the cases.

But it is the anatomo-pathological tumour sample analysis (biopsy via surgery) that gives the rare tumour diagnosis by revealing a very unusual type of cancer cells.

These diffuse lesions affecting axons were initially described there are more than 25 years on the occasion of cerebral pathological examination of patients who died after a long period of post-traumatic vegetative state.