Dictionnaire français - anglais

dihydroxy-propoxy-méthyl-guanine

santé - iate.europa.eu
santé - iate.europa.eu
Carcinoma cell lines sensitive to ganciclovir and radiation in vitro and in vivo... carcinomas, the present studies were undertaken to evaluate in vitro and in vivo therapeutic efficacy and toxicity of herpes simplex virus thymidine kinase (HSV-tk) gene and ganciclovir (GCV) treatment, a widely used prodrug/suicide gene therapy, in human thyroid carcinoma cell lines, FRO and WRO cells, using a means of retrovirus-mediated gene transduction....
santé - core.ac.uk - PDF: citeseerx.ist.psu.edu
Ganciclovir treatment of cytomegalovirus infection of the gastrointestinal tract after marrow transplantation. bone marrow transplant... Interventions: Ganciclovir, 2.5...
 PDF: annals.org
Bystander effect in glioma suicide gene therapy using bone marrow stromal cells ...generated by intratumoral injection of rat bone marrow stromal cells (BMSCs) transduced with the herpes simplex virus-thymidine kinase gene (BMSCtk cells) followed by systemic ganciclovir administration....
Effect of a histone demethylase inhibitor on equine herpesvirus-1 activity in vitro... Equine fetal kidney cells (EFKCs) or isolated peripheral blood leukocytes were treated in vitro with (a) the nucleoside analog ganciclovir; (b) the histone demethylase inhibitor OG-L002; (c) both ganciclovir and OG-L002; or (d) dimethyl sulfoxide (DMSO, vehicle control); and then infected with a clinical...
 PDF: doaj.org
The high-dose, alternate-week intravitreal ganciclovir injections for cytomegalovirus retinitis in acquired immune deficiency syndrome patients on highly active antiretroviral therapyObjectives: To evaluate the efficacy, and complications of the high-dose, alternate-week, intravitreal ganciclovir injection for cytomegaloviral retinitis (CMVR) in acquired immune deficiency syndrome (AIDS) patients on highly active antiretroviral therapy (HAART)....
santé - iate.europa.eu

Publications scientifiques

Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with beta-interferon against herpes simplex virus type 2 in mice.The acyclic nucleoside 9-(1,3-dihydroxy-2- propoxymethyl )guanine (DHPG) and natural mouse interferon beta ( MuIFN -beta) were evaluated for their efficacy alone and in combination against herpes simplex virus type 2 systemic infections in mice....
santé / moyen de production agricole - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Activity of (+)-cyclaradine (sch 31172) against herpes simplex virus in vitro and in vivo.... (+)-Cyclaradine has in vitro activity nearly equivalent to that of phosphonoformate but is significantly less active than acycloguanosine (acyclovir; ACV), trifluorothymidine, or 9-(1,3-dihydroxy-2-propoxymethyl)guanine....
santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Prolonged herpes simplex virus latency in vitro after treatment of infected cells with acyclovir and human leukocyte interferon.... By contrast, the treatment of HSV-1-infected cells with combined IFN-alpha and 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a congener of ACV, failed to establish in vitro virus latency....
santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Toxicity of 3'-azido-3'-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for normal human hematopoietic progenitor cells in vitro.The effects of 3'-azido-3'-deoxythymidine (AZT) and 9-(1,3-dihydroxy-2-propoxymethyl)guanine on myeloid and erythroid colony-forming cells were studied by clonogenic assays....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Inhibition of cellular dna polymerase alpha and human cytomegalovirus-induced dna polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine.The triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine were examined for their inhibitory effect on highly purified cellular DNA polymerase alpha and human cytomegalovirus (Towne strain)-induced...
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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