Disclosed is a novel nitrogen-containing heterocyclic derivative having a specific structure.

Disclosed is a novel nitrogen-containing heterocyclic derivative having a specific structure.

The novel nitrogen-containing heterocyclic derivative is useful as a constituent of the organic electroluminescent device.

A nitrogenous heterocyclic derivative represented by the general formula (I), a pharmacologically acceptable salt thereof, or a prodrug of either.

It is found that a nitrogenated heterocyclic derivative represented by the formula (I) can bind specifically to an NR1/NR2B receptor and can be used as an analgestic agent.

The present invention provides a nitrogen-containing heterocyclic derivative which has ASK1-inhibitory activity and is useful as a prophylactic and/or therapeutic agent for ALS and so on, or a pharmaceutically acceptable salt thereof.