Compounds may be selective for eukaryotic (e.g., human) PDF or prokaryotic PDF.
The invention is directed to a novel class of compounds, which inhibits peptide deformylase, pharmaceutical compositions containing compounds that inhibit peptide deformylase, and method of treating various infections.
PDF inhibitors and novel methods for their use are provided.
Novel PDF inhibitors and novel methods for their use are provided.
The invention relates to novel compounds that are inhibitors of peptidyl deformylase (PDF).
These N-formyl hydroxylamine compounds inhibit peptidyl deformylase (PDF), an enzyme present in prokaryotes .
PDF inhibitors and novel methods for their use are provided.
Such peptide deformylases often contain the sequences of (I) HEXXH, (ii) EGCLS and (iii) GXGXAAXQ.
Novel PDF inhibitors and novel methods for their use are provided.
Nobel PDF inhibitors and novel methods for their use are provided.
This invention relates to an isolated nucleic acid fragment encoding a metalloprotease, more specifically peptide deformylase.
The synthesized peptide deformylase inhibitor can inhibit the protein synthesis of bacteria, and thus kill bacteria.
Novel PDF inhibitors and novel methods for their use are provided.
These N-formyl hydroxylamine compounds inhibit peptidyl deformylase (PDF), an enzyme present in prokaryotes.
Novel PDF inhibitors and novel methods for their use are provided.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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