These granulomas result from an immune reaction, primarily based on cell-mediated immunity.

Oligomeric immunoglobulins joined at the constant region at a specific site provide for enhanced cytolysis in conjunction with complement.

Hepatic cytolysis (or cytolytic hepatitis) refers to a destruction (lysis) of the liver cells.

The subject compositions are shown to be effective in complete cytolysis at substantially lower concentrations than required with the monomeric immunoglobulin.

Under immunosuppressive therapy, the worsening or recurrence of cytolysis is frequent and hepatic lesions may worsen.

The modified polypeptide inhibits cytolysis by the complements of nuclear cells and the release of PGI2 and b-FGF by the complements from HUVEC.

Hepatitis B and C were negative in all the children.

This pathological disorder is called cytolysis syndrome, the development of which explains the appearance of the main symptoms:

Rinsing with a hypotonic solution (such as water) can cause an osmotic shock and a cellular cytolysis (destruction of cells after swelling).

In animal cells which lack a cell wall however, excessive osmotic pressure can result in cytolysis.

The present invention discloses the use of a mutant Leishmania as a suicidal vaccine wherein the mutant Leishmania is responsive to external signals to become porphyric and commit suicidal cytolysis.

Their cytolysis is carried out immuno-indirectly, mainly due to reactions from cellular immunity.

It also prevents the cell from expanding and bursting ( cytolysis ) from osmotic pressure due to a hypotonic environment.

It also prevents the cell from expanding and finally bursting (cytolysis) from osmotic pressure against a hypotonic environment.

Particular aspects show that the signal peptide remains intact on the mature CD18 molecule on ruminant leukocytes rendering these cells susceptible to cytolysis by Lkt.