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Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo.... In vivo, relaxin, at a steady state circulating concentration of approximately 50 ng/ml, inhibited bleomycin-mediated alveolar thickening compared with the vehicle only control group (P < 0.05)....

santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov

Publications scientifiques

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The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.A high circulating concentration of interleukin 6 is associated with increased risk of coronary heart disease....

général - core.ac.uk - PDF: discovery.ucl.ac.uk

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Birth outcomes and il-6, kc and crp levels in pregnant mice following experimentally induced periodontitis....0.030) and (C) circulating concentration of IL-6, KC in serum of pregnant mice with induced periodontitis compared to controls (***p = 0.047)....

général - core.ac.uk - PDF: figshare.com

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Placental growth factor for the prediction of adverse outcomes in patients with suspected preeclampsia or intrauterine growth restrictionThe circulating concentration of PlGF is reported to be lower in patients experiencing preeclampsia and patients delivering a small for gestational age (SGA) neonate....

général - core.ac.uk -

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Assessment of daily activity patterns and biomarkers of pain, inflammation, and stress in lactating dairy cows diagnosed with clinical metritis...objectives of the present case-control study were to assess (1) daily activity patterns (lying time, number of steps, number of lying bouts, and lying bout duration), and (2) circulating concentrations of biomarkers of pain (substance P), inflammation (haptoglobin), and stress (cortisol) in lactating dairy cows diagnosed with clinical metritis....

général - core.ac.uk - PDF: helda.helsinki.fi