Epileptogenic action of cephalosporins ii. epileptogenic action of certain cephalosporins administered intravenously into rats, and antiepileptic effect of certain anticonvulsants in cefazolin-induced seizure... At doses greater than 500 mg/kg, seizure effects were noticed in both EGGs and behavior in the decreasing order of ceftezole, cefotiam, cefazolin and cephaloridine....
Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats....(i.e., cefazolin and ceftezole) are both characterized by the presence of a tetrazole nucleus at position 7 and show a marked chemical similarity to pentylenetetrazole....
Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in bacteroides fragilis.... Cefoperazone showed the highest antibacterial activity, followed by ceftezole, cefazolin, cefamandole, and cephalothin....
Clinical studies on ceftezole in urinary tract infectionsCeftezole (CTZ), a new cephalosporin antibiotic, was clinically evaluated in urinary tract infections including chronic complicated UTI....
