Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described.

The carboxamide derivative provided is one produced by either of the carboxamide derivative production processes.

The N-acyl 2-oxindole-1-carboxamide intermediate may be converted to the 2-oxindole-1-carboxamide without isolation.

Compounds of the invention include N-(3-(trifluoromethyl)phenyl )-2-methyl-1-(3-morpholinopropyl )-5-phenyl-1 H-pyrrole-3-carboxamide, as well as other 2-phenyl-pyrrole carboxamide derivates and indole carboxamide derivatives.

Preferably, the coolant is a cyclic carboxamide such as N- ethyl-p-menthane-3 -carboxamide.

The invention is directed to novel indazole carboxamide derivatives.

The invention is directed to novel indole carboxamide compounds.

The invention is directed to novel indole carboxamide derivatives.

Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described.

The other process for producing a carboxamide derivative comprises reacting the carboxamide with any of monohaloalkylcarboxylic acids and salts thereof.

The invention is directed to novel indazole carboxamide derivatives.

  By reacting the N-(1-hydroxyethyl)carboxamide compound with an alcohol in the presence of an acid catalyst, the N-(1-alkoxyethyl)carboxamide compound is obtained.

A process for the product of a 2,3-cis-dihydroxycycloalkane-1-carboxamide, comprises dihydroxylation of the corresponding cycloalkene-1-carboxamide.

The invention is directed to novel indole carboxamide derivatives.

The invention is directed to novel azaindole and azaindazole carboxamide derivatives.